TY - JOUR
T1 - A systematic review and meta-analysis of randomized controlled trials of cognitive behavioral therapy for hemodialysis patients with depression
AU - NG, Chong Zheng
AU - TANG, Sydney C.
AU - CHAN, Meanne
AU - TRAN, Bach X.
AU - HO, Cyrus S.
AU - TAM, Wilson W.
AU - HO, Roger C.
PY - 2019/11
Y1 - 2019/11
N2 - Objective: The aim of this meta-analysis was to examine the efficacy of cognitive behavioral therapy (CBT) for hemodialysis patients with comorbid depression and to identify which other aspects, including anxiety and quality of life, can be improved through intervention. Methods: A systematic literature review was performed using multiple databases (PubMed, EMBase, PsycINFO, CENTRAL). The inclusion criteria included randomized controlled trials (RCTs) of CBT conducted in hemodialysis patients with depression. Study reporting quality was assessed with the Cochrane tool and Review Manager version 5.3 was used to obtain pooled results. Results: Eight RCTs, with a total sample size of 540 participants, met the inclusion criteria. Compared with control groups, the CBT groups had statistically significant improvements in depression (standardized mean differences [SMD] = −0.68, 95% confidence interval [CI] (−0.94 to −0.42), P < .001), anxiety (SMD = −0.99, 95%CI (−1.99 to 0.00), P = .05) and quality of life (SMD = 0.34, 95%CI (0.13 to 0.54), P < .001). Conclusions: The results of this meta-analysis showed that CBT could have an effective role in reducing symptoms of depression and anxiety as well as improving quality of life in hemodialysis patients with comorbid depression.
AB - Objective: The aim of this meta-analysis was to examine the efficacy of cognitive behavioral therapy (CBT) for hemodialysis patients with comorbid depression and to identify which other aspects, including anxiety and quality of life, can be improved through intervention. Methods: A systematic literature review was performed using multiple databases (PubMed, EMBase, PsycINFO, CENTRAL). The inclusion criteria included randomized controlled trials (RCTs) of CBT conducted in hemodialysis patients with depression. Study reporting quality was assessed with the Cochrane tool and Review Manager version 5.3 was used to obtain pooled results. Results: Eight RCTs, with a total sample size of 540 participants, met the inclusion criteria. Compared with control groups, the CBT groups had statistically significant improvements in depression (standardized mean differences [SMD] = −0.68, 95% confidence interval [CI] (−0.94 to −0.42), P < .001), anxiety (SMD = −0.99, 95%CI (−1.99 to 0.00), P = .05) and quality of life (SMD = 0.34, 95%CI (0.13 to 0.54), P < .001). Conclusions: The results of this meta-analysis showed that CBT could have an effective role in reducing symptoms of depression and anxiety as well as improving quality of life in hemodialysis patients with comorbid depression.
UR - http://www.scopus.com/inward/record.url?scp=85072193492&partnerID=8YFLogxK
U2 - 10.1016/j.jpsychores.2019.109834
DO - 10.1016/j.jpsychores.2019.109834
M3 - Journal Article (refereed)
C2 - 31525637
AN - SCOPUS:85072193492
SN - 0022-3999
VL - 126
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
M1 - 109834
ER -
