Atopic eczema and the home environment

N. J. MCNALLY, H. C. WILLIAMS, David Rosser PHILLIPS

    Research output: Journal PublicationsJournal Article (refereed)

    51 Citations (Scopus)

    Abstract

    Background: There is strong evidence to suggest that the prevalence of atopic eczema is increasing in developed countries. Environmental factors have been implicated in the disease. Objectives: This descriptive case-control study sheds light on the possible association between atopic eczema in school children and various home environmental factors, and generates hypotheses for further studies. Methods: The study uses data on reported atopic eczema symptoms collected via a cross-sectional parental postal survey (n = 1350) in Nottingham, U.K. Estimates of the risk of reported eczema associated with various home environmental factors were calculated by means of odds ratios (OR), along with population attributable risk percentages. Results: The study showed statistically significant associations between atopic eczema symptoms and dampness in the home [OR 1.40; 95% confidence interval (CI) 1.00-1.97], the use of a radiator to heat the child's bedroom (OR 1.50; 95% CI 1.05-2.16) and the use of synthetic pillows (OR 1.51; 95% CI 1.01-2.28). Frequent vacuuming in the home was associated with a decreased prevalence of atopic eczema (OR 0.74; 95% CI 0.58-0.94). The associations with dampness in the home, synthetic pillows and frequency of vacuuming were not altered significantly after adjustment for age, sex and socio-economic status. Population attributable risk percentages for the use of a radiator and synthetic pillows indicate that although the relative risk estimates for these factors may be small, the population impact of these factors is considerable (26% and 28%, respectively), owing to the high prevalence of exposure to these factors among this group of school children. Conclusions: Further research is needed to confirm these associations and additional research is needed to see whether they might be causative. Practical public health advice about the importance of controlling the home environment may then be targeted at families with atopic eczema.
    Original languageEnglish
    Pages (from-to)730-736
    Number of pages7
    JournalBritish Journal of Dermatology
    Volume145
    Issue number5
    DOIs
    Publication statusPublished - 1 Jan 2001

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    Atopic Dermatitis
    Odds Ratio
    Confidence Intervals
    Population
    Eczema
    Research
    Developed Countries
    Case-Control Studies
    Public Health
    Hot Temperature
    Economics

    Cite this

    MCNALLY, N. J. ; WILLIAMS, H. C. ; PHILLIPS, David Rosser. / Atopic eczema and the home environment. In: British Journal of Dermatology. 2001 ; Vol. 145, No. 5. pp. 730-736.
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    title = "Atopic eczema and the home environment",
    abstract = "Background: There is strong evidence to suggest that the prevalence of atopic eczema is increasing in developed countries. Environmental factors have been implicated in the disease. Objectives: This descriptive case-control study sheds light on the possible association between atopic eczema in school children and various home environmental factors, and generates hypotheses for further studies. Methods: The study uses data on reported atopic eczema symptoms collected via a cross-sectional parental postal survey (n = 1350) in Nottingham, U.K. Estimates of the risk of reported eczema associated with various home environmental factors were calculated by means of odds ratios (OR), along with population attributable risk percentages. Results: The study showed statistically significant associations between atopic eczema symptoms and dampness in the home [OR 1.40; 95{\%} confidence interval (CI) 1.00-1.97], the use of a radiator to heat the child's bedroom (OR 1.50; 95{\%} CI 1.05-2.16) and the use of synthetic pillows (OR 1.51; 95{\%} CI 1.01-2.28). Frequent vacuuming in the home was associated with a decreased prevalence of atopic eczema (OR 0.74; 95{\%} CI 0.58-0.94). The associations with dampness in the home, synthetic pillows and frequency of vacuuming were not altered significantly after adjustment for age, sex and socio-economic status. Population attributable risk percentages for the use of a radiator and synthetic pillows indicate that although the relative risk estimates for these factors may be small, the population impact of these factors is considerable (26{\%} and 28{\%}, respectively), owing to the high prevalence of exposure to these factors among this group of school children. Conclusions: Further research is needed to confirm these associations and additional research is needed to see whether they might be causative. Practical public health advice about the importance of controlling the home environment may then be targeted at families with atopic eczema.",
    author = "MCNALLY, {N. J.} and WILLIAMS, {H. C.} and PHILLIPS, {David Rosser}",
    year = "2001",
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    doi = "10.1046/j.1365-2133.2001.04474.x",
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    Atopic eczema and the home environment. / MCNALLY, N. J.; WILLIAMS, H. C.; PHILLIPS, David Rosser.

    In: British Journal of Dermatology, Vol. 145, No. 5, 01.01.2001, p. 730-736.

    Research output: Journal PublicationsJournal Article (refereed)

    TY - JOUR

    T1 - Atopic eczema and the home environment

    AU - MCNALLY, N. J.

    AU - WILLIAMS, H. C.

    AU - PHILLIPS, David Rosser

    PY - 2001/1/1

    Y1 - 2001/1/1

    N2 - Background: There is strong evidence to suggest that the prevalence of atopic eczema is increasing in developed countries. Environmental factors have been implicated in the disease. Objectives: This descriptive case-control study sheds light on the possible association between atopic eczema in school children and various home environmental factors, and generates hypotheses for further studies. Methods: The study uses data on reported atopic eczema symptoms collected via a cross-sectional parental postal survey (n = 1350) in Nottingham, U.K. Estimates of the risk of reported eczema associated with various home environmental factors were calculated by means of odds ratios (OR), along with population attributable risk percentages. Results: The study showed statistically significant associations between atopic eczema symptoms and dampness in the home [OR 1.40; 95% confidence interval (CI) 1.00-1.97], the use of a radiator to heat the child's bedroom (OR 1.50; 95% CI 1.05-2.16) and the use of synthetic pillows (OR 1.51; 95% CI 1.01-2.28). Frequent vacuuming in the home was associated with a decreased prevalence of atopic eczema (OR 0.74; 95% CI 0.58-0.94). The associations with dampness in the home, synthetic pillows and frequency of vacuuming were not altered significantly after adjustment for age, sex and socio-economic status. Population attributable risk percentages for the use of a radiator and synthetic pillows indicate that although the relative risk estimates for these factors may be small, the population impact of these factors is considerable (26% and 28%, respectively), owing to the high prevalence of exposure to these factors among this group of school children. Conclusions: Further research is needed to confirm these associations and additional research is needed to see whether they might be causative. Practical public health advice about the importance of controlling the home environment may then be targeted at families with atopic eczema.

    AB - Background: There is strong evidence to suggest that the prevalence of atopic eczema is increasing in developed countries. Environmental factors have been implicated in the disease. Objectives: This descriptive case-control study sheds light on the possible association between atopic eczema in school children and various home environmental factors, and generates hypotheses for further studies. Methods: The study uses data on reported atopic eczema symptoms collected via a cross-sectional parental postal survey (n = 1350) in Nottingham, U.K. Estimates of the risk of reported eczema associated with various home environmental factors were calculated by means of odds ratios (OR), along with population attributable risk percentages. Results: The study showed statistically significant associations between atopic eczema symptoms and dampness in the home [OR 1.40; 95% confidence interval (CI) 1.00-1.97], the use of a radiator to heat the child's bedroom (OR 1.50; 95% CI 1.05-2.16) and the use of synthetic pillows (OR 1.51; 95% CI 1.01-2.28). Frequent vacuuming in the home was associated with a decreased prevalence of atopic eczema (OR 0.74; 95% CI 0.58-0.94). The associations with dampness in the home, synthetic pillows and frequency of vacuuming were not altered significantly after adjustment for age, sex and socio-economic status. Population attributable risk percentages for the use of a radiator and synthetic pillows indicate that although the relative risk estimates for these factors may be small, the population impact of these factors is considerable (26% and 28%, respectively), owing to the high prevalence of exposure to these factors among this group of school children. Conclusions: Further research is needed to confirm these associations and additional research is needed to see whether they might be causative. Practical public health advice about the importance of controlling the home environment may then be targeted at families with atopic eczema.

    UR - http://commons.ln.edu.hk/sw_master/1775

    U2 - 10.1046/j.1365-2133.2001.04474.x

    DO - 10.1046/j.1365-2133.2001.04474.x

    M3 - Journal Article (refereed)

    VL - 145

    SP - 730

    EP - 736

    JO - British Journal of Dermatology

    JF - British Journal of Dermatology

    SN - 0007-0963

    IS - 5

    ER -