Differential effects of mindfulness and grit on positive mental health outcomes in major depressive and bipolar disorders : A moderation analysis using an ecological momentary assessment approach

  • Joyce Xu Hao JIN
  • , Heidi Ka Ying LO*
  • , Iris Wai Tung TSUI
  • , Ting Kin NG
  • , Ka Fai CHUNG
  • , Suet Ying YUEN
  • , Fiona Yan Yee HO
  • , Corine Sau Man WONG
  • , Chit Tat LEE
  • , Chun Yin POON
  • , Kayla M. TEOPIZ
  • , Christine DRI
  • , Roger S. MCINTYRE
  • *Corresponding author for this work

Research output: Journal PublicationsJournal Article (refereed)peer-review

1 Citation (Scopus)

Abstract

Background
Holistic management of persons living with Major Depressive Disorder (MDD) and Bipolar Disorder (BD) invites the need for evaluation of positive mental health (PMH; pleasure attainment and meaning-in-life), alongside conventional measures of psychopathology. The aforementioned dimensions of PMH involve aspects of mindfulness and grit. Herein, we evaluate these aspects using ecological momentary assessment (EMA) approach.

Methods
This study investigated how positive psychological traits interact with negative affect (NA) to affect PMH in persons with MDD (n = 29), BD (n = 29), and healthy controls (HCs) (n = 30). Self-reported NA, pleasure attainment, and meaning-in-life were captured five times a day during a two-week observation period. Mindfulness and grit were assessed using the Five-Facet Mindfulness Questionnaire and Grit-Scale-Short, respectively. Moderation and simple-slope-analyses were conducted.

Results
A total of 4632 EMA observations were made. Moderated-moderation-analyses indicated significant differences between groups. Lower NA levels significantly potentiated the mindfulness-life meaning relationship in the MDD group (b = −0.315, p = .037), but not in BD and HC. Meanwhile, higher grit levels significantly attenuated NA's negative impact on pleasure attainment in the BD (b = 0.247, p = .034), but not in the MDD/HC group.

Limitations
The use of trait measurements limited direct state comparisons.

Conclusion
Lower NA levels augmented the positive effects of measures of mindfulness on life-meaning in MDD. Higher grit levels mitigated against reduction in pleasure attainment due to NA in BD. Our results underscore the complex interactions between measures of positive psychological traits and PMH in MDD and BD.
Original languageEnglish
Article number119969
JournalJournal of Affective Disorders
Volume391
Early online date23 Jul 2025
DOIs
Publication statusPublished - 15 Dec 2025

Bibliographical note

Publisher Copyright:
© 2025 Elsevier B.V.

Funding

The study was supported by the Seed Fund for Basic Research of the University of Hong Kong (grant number: 2201101137). The funders had no role in study design, data collection, data analysis, interpretation of the data, manuscript preparation or journal submission.

Keywords

  • Experience sampling method (ESM)
  • Major depressive disorder
  • Bipolar disorder
  • Mindfulness
  • Grit
  • Positive mental health

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