The recent challenge issued by the HFES President emphasizes the need for members and professionals of the Human Factors and Ergonomics community to remain relevant to society at large in spite of the challenges we face as a professional society (Marras, 2015). One characteristic of our present and future as a society is our existence in a world of increasing globalization. Consequently, it is appropriate that we grow our awareness of the culture of HF/E around the world in order to facilitate increased reception of the services we are able to offer and promote intercultural collaboration. This panel brings professionals from academia and industry around the world to bring their perspectives on unique challenges and approaches to HF/E in an international setting. These global perspectives span industries, countries, and attitudes and behaviors from around the world. The panel will first present their observations on the unique aspects of their cultural experiences and then engage attendees in a discussion with the aim of equipping them to adopt a more effective global mindset towards their HF/E endeavors.