Is there a geographical variation in eczema prevalence in the U.K.? Evidence from the 1958 British birth cohort study

N. J. MCNALLY, H. C. WILLIAMS, David Rosser PHILLIPS, D. P. STRACHAN

    Research output: Journal PublicationsJournal Article (refereed)

    31 Citations (Scopus)

    Abstract

    Some studies have suggested that the prevalence of atopic eczema may vary between geographical regions. This descriptive study investigates the regional and subregional geography of reported and examined eczema prevalence at the age of 7, 11 and 16 years in Britain using data from the 1958 birth cohort study (n = 828). Estimates of the relative risk of reported eczema associated with residence in each region of the country were calculated and the regional distribution of reported and examined eczema prevalence was compared. The reported prevalence of eczema was mapped at the smaller county level. Comparisons were made with the county-level distribution of asthma and hay fever prevalence. The study showed a marked and statistically significant variation in eczema prevalence across the regions in Britain which was present for examined as well as reported eczema. The highest risk was associated with four regions: North Midlands; Eastern; London and the South- East; and Southern. This regional pattern was not altered significantly after adjustment for social class and family size. The geographical distribution of eczema prevalence was largely maintained when analysed at the county level. Few similarities were found between the county-level distribution of eczema prevalence and that for asthma and hay fever. Explanations for this strong regional variation now need to be sought in terms of environmental and life- style associations.
    Original languageEnglish
    Pages (from-to)712-720
    Number of pages9
    JournalBritish Journal of Dermatology
    Volume142
    Issue number4
    DOIs
    Publication statusPublished - 1 Jan 2000

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    Eczema
    Cohort Studies
    Parturition
    Seasonal Allergic Rhinitis
    Asthma
    Geography
    Atopic Dermatitis
    Social Class
    Life Style

    Cite this

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    title = "Is there a geographical variation in eczema prevalence in the U.K.? Evidence from the 1958 British birth cohort study",
    abstract = "Some studies have suggested that the prevalence of atopic eczema may vary between geographical regions. This descriptive study investigates the regional and subregional geography of reported and examined eczema prevalence at the age of 7, 11 and 16 years in Britain using data from the 1958 birth cohort study (n = 828). Estimates of the relative risk of reported eczema associated with residence in each region of the country were calculated and the regional distribution of reported and examined eczema prevalence was compared. The reported prevalence of eczema was mapped at the smaller county level. Comparisons were made with the county-level distribution of asthma and hay fever prevalence. The study showed a marked and statistically significant variation in eczema prevalence across the regions in Britain which was present for examined as well as reported eczema. The highest risk was associated with four regions: North Midlands; Eastern; London and the South- East; and Southern. This regional pattern was not altered significantly after adjustment for social class and family size. The geographical distribution of eczema prevalence was largely maintained when analysed at the county level. Few similarities were found between the county-level distribution of eczema prevalence and that for asthma and hay fever. Explanations for this strong regional variation now need to be sought in terms of environmental and life- style associations.",
    author = "MCNALLY, {N. J.} and WILLIAMS, {H. C.} and PHILLIPS, {David Rosser} and STRACHAN, {D. P.}",
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    Is there a geographical variation in eczema prevalence in the U.K.? Evidence from the 1958 British birth cohort study. / MCNALLY, N. J.; WILLIAMS, H. C.; PHILLIPS, David Rosser; STRACHAN, D. P.

    In: British Journal of Dermatology, Vol. 142, No. 4, 01.01.2000, p. 712-720.

    Research output: Journal PublicationsJournal Article (refereed)

    TY - JOUR

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    AU - WILLIAMS, H. C.

    AU - PHILLIPS, David Rosser

    AU - STRACHAN, D. P.

    PY - 2000/1/1

    Y1 - 2000/1/1

    N2 - Some studies have suggested that the prevalence of atopic eczema may vary between geographical regions. This descriptive study investigates the regional and subregional geography of reported and examined eczema prevalence at the age of 7, 11 and 16 years in Britain using data from the 1958 birth cohort study (n = 828). Estimates of the relative risk of reported eczema associated with residence in each region of the country were calculated and the regional distribution of reported and examined eczema prevalence was compared. The reported prevalence of eczema was mapped at the smaller county level. Comparisons were made with the county-level distribution of asthma and hay fever prevalence. The study showed a marked and statistically significant variation in eczema prevalence across the regions in Britain which was present for examined as well as reported eczema. The highest risk was associated with four regions: North Midlands; Eastern; London and the South- East; and Southern. This regional pattern was not altered significantly after adjustment for social class and family size. The geographical distribution of eczema prevalence was largely maintained when analysed at the county level. Few similarities were found between the county-level distribution of eczema prevalence and that for asthma and hay fever. Explanations for this strong regional variation now need to be sought in terms of environmental and life- style associations.

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