Merely Possessing a Placebo Analgesic Improves Analgesia Similar to Using the Placebo Analgesic

Wai Lan Victoria YEUNG*, Andrew L. GEERS, Luana COLLOCA

*Corresponding author for this work

Research output: Journal PublicationsJournal Article (refereed)


Placebo analgesia studies generally reported that the actual use of a placebo analgesic reduces pain. Yeung, Geers and Kam (2019) found that the mere possession (without use) of a placebo analgesic also reduces pain.

We investigated the relative effectiveness of using versus possessing a placebo analgesic on pain outcomes.

In Study 1a, 120 healthy adults were randomized to either the experimental (EXP) conditions (EXP1: used a placebo analgesic cream, EXP2: possessed a placebo analgesic cream) or control (CO) conditions (CO1: possessed a sham cream, CO2: no cream). All participants underwent a cold pressor test (CPT). Study 1b further delineated the effect of possession from the effect of use. Sixty healthy adults were randomized to either the placebo-possession condition (merely possessed a placebo analgesic cream) or the placebo-possession-use condition (possessed and used a placebo analgesic cream). All participants did a CPT.

In Study 1a, as expected, a placebo effect was found—participants who used a placebo analgesic cream showed better pain outcomes than the two CO groups. Surprisingly, participants who merely possessed a placebo analgesic cream performed equally well as those who actually used it. In Study 1b, participants in the two conditions did not differ in most pain outcomes. Participants who possessed and used a placebo analgesic cream only showed slightly more reduction in pain intensity compared to participants who merely possessed the placebo analgesic cream.

Our results suggest that merely possessing a placebo analgesic could enhance pain outcomes similar to that of applying the placebo analgesic.
Original languageEnglish
Article numberkaaa007
JournalAnnals of Behavioral Medicine
Early online date20 Mar 2020
Publication statusE-pub ahead of print - 20 Mar 2020


Bibliographical note

The research was supported by the General Research Fund (GRF13600617) awarded by the Research Grants Council, University Grants Committee, Hong Kong to V.W.L.Y. We thank Mr. Tam Pui Chuen and Mr. Eric Kenson Yau for providing research assistance.


  • placebo effect
  • mere possession
  • analgesia
  • pain intensity

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