In this paper, we study the resource management problem in Direct Sequence-Wideband Code Division Multiple Access (DS-WCDMA) systems. The control variables, transmission power, and transmission rate for resource management are considered. Three meta-heuristic techniques, Genetic Algorithms (GA), Simulated Annealing (SA), and Tabu Search (TS), are utilized to solve this optimization problem. Also, a nonlinear programming technique, Generalized Reduced Gradient (GRG) method, is adopted to compare with the three meta-heuristic techniques. Two approaches, the single objective approach and the multiobjective approach, are used in the simulation. The results obtained by GA, SA, TS, and GRG are compared in a single objective approach. In a multiobjective approach, Multiobjective Genetic Algorithm (MOGA) is employed to compare with the other two well-known multiobjective evolutionary algorithms (MOEAs), Pareto Archived Evolution Strategy (PAES) and Micro-Genetic Algorithms (MICRO-GA). Two scenarios, scenario (a): 25 users and scenario (b): 50 users, are considered for both approaches. The simulation results of a single objective approach show that GA outperforms SA, TS, and GRG in the two scenarios. Also, the simulation results of a multiobjective approach show that MOGA outperforms PAES and MICRO-GA, and obtains nondominated trade-off solutions with better convergence and diversity between trade minimization of total power and maximization of total rate in two scenarios.