Short communication: Two steps Synthesis of a BODIPY carboxylic-Curcumin

Siukan LAW*, Albert Wingnang LEUNG, Chuanshan XU

*Corresponding author for this work

Research output: Other PublicationsOther Article

Abstract

Boron dipyrromethene (BODIPY) carboxylic acid belong to a family of organoboron compounds and widely as fluorescent dye while curcumin is the traditional Chinese medicine to treat various diseases. Curcumin has a maximum absorption peak at wavelength 430 nm but its wavelength perhaps not long enough for photodynamic therapy or other biological applications. Organic synthesis is the major studied in this short communication, so we proposed a synthetic method linking the Boron dipyrromethene (BODIPY) carboxylic acid and curcumin to increase its absorption wavelength. The synthesized product, "BODIPY carboxylic-Curcumin" with 11% yield and characterized by 1H NMR, 13C NMR, HRMS and HPLC. It’s also determined by Ultraviolet-visible (UV-Vis) spectroscopy. This preliminary results as an important starting to decide it for further investigation.
Original languageEnglish
Pages1403-1411
Number of pages9
Volume11
No.9
Specialist publicationJournal of Materials and Environmental Science
Publication statusPublished - Sep 2020

Bibliographical note

This work was supported by the Innovation and Technology Fund of Shenzhen (JCYJ20170307165459562).

Keywords

  • Boron dipyrromethene carboxylic acid
  • BODIPY
  • Curcumin
  • Organic synthesis

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