TY - JOUR
T1 - Synchronization measurement of multiple neuronal populations
AU - LI, Xiaoli
AU - CUI, Dong
AU - JIRUSKA, Premysl
AU - FOX, John E.
AU - YAO, Xin
AU - JEFFERYS, John G. R.
PY - 2007/12
Y1 - 2007/12
N2 - The purpose of the present paper is to develop a method, based on equal-time correlation, correlation matrix analysis and surrogate resampling, that is able to quantify and describe properties of synchronization of population neuronal activity recorded simultaneously from multiple sites. Initially, Lorenz-type oscillators were used to model multiple time series with different patterns of synchronization. Eigenvalue and eigenvector decomposition was then applied to identify "clusters" of locally synchronized activity and to calculate a "global synchronization index." This method was then applied to multichannel data recorded from an in vitro model of epileptic seizures. The results demonstrate that this novel method can be successfully used to analyze synchronization between multiple neuronal population series. Copyright © 2007 The American Physiological Society.
AB - The purpose of the present paper is to develop a method, based on equal-time correlation, correlation matrix analysis and surrogate resampling, that is able to quantify and describe properties of synchronization of population neuronal activity recorded simultaneously from multiple sites. Initially, Lorenz-type oscillators were used to model multiple time series with different patterns of synchronization. Eigenvalue and eigenvector decomposition was then applied to identify "clusters" of locally synchronized activity and to calculate a "global synchronization index." This method was then applied to multichannel data recorded from an in vitro model of epileptic seizures. The results demonstrate that this novel method can be successfully used to analyze synchronization between multiple neuronal population series. Copyright © 2007 The American Physiological Society.
UR - http://www.scopus.com/inward/record.url?scp=37549056503&partnerID=8YFLogxK
U2 - 10.1152/jn.00977.2007
DO - 10.1152/jn.00977.2007
M3 - Journal Article (refereed)
SN - 0022-3077
VL - 98
SP - 3341
EP - 3348
JO - Journal of Neurophysiology
JF - Journal of Neurophysiology
IS - 6
ER -