This study aimed at validating the Curiosity and Exploration Inventory-II (CEI-II; Kashdan et al., 2009) in a Chinese context. A total of 294 Chinese first-year undergraduate students in Hong Kong completed the CEI-II and measures of satisfaction with university life, the Big Five personality traits, and human values. The results of exploratory structural equation modeling, parallel analysis, and confirmatory factor analysis supported a 1-factor solution and did not replicate the original 2-factor structure. Time invariance of the 1-factor structure was obtained among 242 participants who completed the questionnaires again after 4 months. The latent means and correlation indicated that curiosity as measured by the CEI-II was quite stable over the period of investigation. The CEI-II was found to be positively correlated with satisfaction with university life, extraversion, agreeableness, conscientiousness, openness to experience, and openness to change values, but negatively with neuroticism and conservation values. The results of hierarchical multiple regression analyses showed that the CEI-II score had incremental validity above and beyond the Big Five personality traits in predicting human values and satisfaction with university life.